Welcome to Your TotalRx Update! Hey there! Grab a coffee and dive into the latest healthcare breakthroughs and wallet-saving tips. At TotalRx.net, we’re here to slice through the noise—and the greed—to bring you affordable meds and top-notch info. Let’s roll!
Top Health News: FDA Approvals Spotlight
The FDA’s been busy, and we’re unpacking the latest approvals that could change lives—and budgets. September 2025 delivered big wins for rare and chronic conditions, plus a heads-up on GLP-1 risks. Here’s the full scoop:
- Elamipretide (Forzinity) – Approved September 19, 2025 A first-ever treatment for Barth syndrome, a rare genetic disorder affecting muscle strength in patients weighing at least 45 kg (about 99 lbs). This subcutaneous injection targets mitochondria to boost cardiac and skeletal function. With only ~200 cases worldwide, it’s a game-changer, though initial costs may be high. Our advocates can help with assistance programs.
- Tolebrutinib – Priority Review Granted, Decision Pending Fast-tracked for non-relapsing secondary progressive multiple sclerosis (nrSPMS), this oral BTK inhibitor crosses the blood-brain barrier to slow disability progression in patients beyond relapses. MS drugs often cost $50K+ annually, but TotalRx’s negotiation team is ready to secure better deals—enroll now to prepare.
- Imlunestrant (Inluriyo) – Approved September 25, 2025 A next-gen oral estrogen receptor degrader for ER-positive, HER2-negative advanced breast cancer in adults who’ve progressed on prior endocrine therapy. It’s part of a September oncology boom, including new treatments for bladder and prostate cancers.6 Biosimilars are on the horizon to help lower costs.
October Watchlist: PDUFA dates are set for acute myeloid leukemia, chronic rhinosinusitis with nasal polyps, and lupus nephritis treatments, potentially expanding affordable care options. See the FDA’s 2025 novel approvals list for more.
GLP-1 Drug Alert: Eye on the Risks GLP-1 meds like Ozempic (semaglutide) are under scrutiny beyond their diabetes and weight-loss benefits. A February 2025 study of nine patients flagged nonarteritic anterior ischemic optic neuropathy (NAION), a rare vision loss condition, as a potential side effect. The European Medicines Agency labeled NAION “very rare” for Ozempic, Rybelsus, and Wegovy in June 2025. A July 2025 JAMA Ophthalmology study found up to 7x higher NAION risk for users vs. other diabetes drugs, though absolute risk is low (~1 in 1,000). A June study also noted a slight age-related macular degeneration risk. On these meds? Report vision changes to your doctor immediately. We’re tracking impacts on coverage and costs.
Big Savings with TotalRx.net
Why Pay More? With deductibles averaging $590 and albuterol inhalers costing $100 out-of-pocket, greedy drug prices hit hard. “Cut costs, not wallets!” Our TotalRx Savings Card saves you up to 80% at 70,000+ pharmacies nationwide. Members can Print, email, or download it today!
How It Works
- Compare prices: Drug costs vary by pharmacy—shop smart.
- No coupon needed: Show Card at pickup for instant savings.
- No limits: Use it for all your meds, from generics to specialty scripts.
For High-Cost Meds Got prescriptions over $300? Our U.S.-based advocates negotiate the best prices for you.
- Special Group enrollment subscriptions: Details? Call 214-850-1069
- No deductibles: Save big on diabetes meds, specialty drugs, and more.
Call us at 214-850-1069 with questions or to get started.
Today’s Most Interesting Rx Fact
Did you know the first antibiotic, penicillin, was discovered by accident in 1928 when Alexander Fleming noticed mold killing bacteria in a petri dish? Fast forward to 2025, and antibiotics like amoxicillin remain among the most prescribed drugs in the U.S.—yet their average retail price can still hit $20-$50 without insurance. TotalRx’s discount card can drop that to pennies, proving even old-school meds benefit from modern savings!
Pro Tip of the Month
Compare pharmacy prices before filling your script—then use your TotalRx.net Savings Card at checkout to shut down greedy prices. Savings made simple!
Stay Healthy, Save Smart We’re here to make healthcare affordable and keep you looped in on breakthroughs like these FDA approvals. Got a topic you’d like us to cover? Reply or give us a call. Talk soon!
Stay well, The TotalRx.net Team
P.S. Ready to squash high drug costs? Enroll now!
Contact Us 📞 214-850-1069 🌐 totalrx.net 📧 mreagan@benefitfixes.com
